Your CRO Partner for Transformative Research Excellence

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Nutraceuticals

Services

Preclinical Studies

Our preclinical study services are designed to support the development of new pharmaceuticals compounds, providing essential data for regulatory approval and ensuring the safety and efficacy of new drugs.

Animal Studies

Animal studies are scientific investigations that involve animals as subjects. These studies play a crucial role in advancing our understanding of biology, medicine, psychology, and other fields.

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Toxicology studies

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Microbiology and Genotoxicity

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Efficacy studies

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Biocompatibility studies

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Immunization studies/Antibody production

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Bioassays/pharmacopeia studies (USP, BP, EP, IP)

Toxicology Studies

Toxicology studies are scientific investigations that aim to assess the harmful effects of substances on living organisms. These studies are crucial for understanding the toxicity of various chemicals, drugs, pollutants, and other substances.

Acute & Sub-Acute Toxicity

  • Oral (Dietary / Gavage), SC, IM, IV, IP, Inhalation
  • Dermal / Eye Irritation
  • Skin sensitization

Chronic & Sub-Chronic Toxicity

  • Repeated dose 28/90 day
  • Chronic study (6 months)
  • Reproductive toxicity studies

Genotoxicity

  • AMES Test (Salmonella & E coli)
  • In Vitro / In vivo Micronucleus test
  • In Vitro / In vivo Chromosomal aberration test

Alternatives to Animal Studies (Under Validation)

  • In Vitro Eye irritation (RhCE)
  • In Vitro Skin irritation (RhE)

CRO Products

Our preclinical study services are designed to support the development of new pharmaceuticals compounds, providing essential data for regulatory approval and ensuring the safety and efficacy of new drugs.

S.No. Chemical/Intermediates Compound class CAS No. Maximum quantity prepared Data available Status
1 2-Methylquinoline-6-carboxylic acid Quinoline 635-80-3 25 Kg COA/NMR/Purity Comm. scale
2 5-Bromo-2-chloro-1H-benzimidazole Imidazole 683240-76-8 100 g COA/NMR/Purity Lab scale
3 1-Butyl-3-methylimidazolium chloride/ BMIMCl- Imidazole 79917-90-1 1Kg COA/NMR/Purity Pilot scale
4 1-Butyl-2,3-Dimethylimidazolium Chloride Imidazole 98892-75-2 1Kg COA/NMR/Purity Pilot scale
5 Methyl -cbz-amino(Diethoxyphosphoryl) acetate aliphatic-phosphorous 114684-69-4 20 Kg COA/NMR/Purity Pilot scale
6 2-bromo-1,4-difluoro-3-nitrobenzene Fluro derivatives Not available 100 g COA/NMR/Purity Lab scale
7 2,3,6-trifluoroaniline Fluro derivatives 67815-56-9 100 g COA/NMR/Purity Lab scale
8 4-(Bromomethyl)-3-fluorobenzonitrile Fluro derivatives 105942-09-4  250 g COA/NMR/Purity Lab scale
9 4-Fluoro-4'-hydroxybenzophenone Fluro derivatives 25913-05-7 1Kg COA/NMR/Purity Pilot scale
10 2-nitro-5-(trifluoromethyl)aniline Fluro derivatives 402-14-2 100 g COA/NMR/Purity Lab scale
11 4-nitro-5-(trifluoromethyl)aniline Fluro derivatives 179062-05-6 50g COA/NMR/Purity Lab scale
12 1-bromo-2,5-difluoro-4-nitrobenzene Fluro derivatives 167415-27-2 50g COA/NMR/Purity Lab scale
13 1,2,3-Trifluoro-5-nitrobenzene Fluro derivatives 66684-58-0 50 g COA/NMR/Purity Lab scale
14 4-Fluoro-3-​phenoxybenzaldehyde Fluro derivatives 68359-57-9 2 Kg COA/NMR/Purity Pilot scale
15 1H-Indazole-5-sulfonyl chloride sulphonyl chlorides 599183-35-4 5 g COA/NMR/Purity Lab scale
16 2-Fluoro-6-methoxybenzenesulphonyl chloride sulphonyl chlorides 1176126-31-0 100 g COA/NMR/Purity Lab scale
17 2-methylpyrimidine-4-carbaldehyde pyrimidine 1004-17-7 5 Kg COA/NMR/Purity Pilot scale
18 4,6-Dimethoxypyrimidine-2-carbonitrile pyrimidine 139539-63-2 1Kg COA/NMR/Purity Pilot scale
19 4-bromo 2-chloro pyrimidine pyrimidine 885702-34-1 25 g COA/NMR/Purity Lab scale
20 3-hydroxy pyridine 2-carboxaldehyde pyridine 1849-55-4 25 g COA/NMR/Purity Lab scale
21 3,4 dihydro-4-oxo-1(2H)-pyridinecarboxylic acid benzyl ester pyridine 185847-84-1 1 Kg COA/NMR/Purity Pilot scale
22 Benzo[d]pyridazine pyridine 253-52-1 500 g COA/NMR/Purity Lab scale
23 6-Bromo-5-chloropicolinic acid pyridine 1214328-42-3 100 g COA/NMR/Purity Lab scale
24 1,3-Dihydroxynaphthalene Polycylic 132-86-5 1 Kg COA/NMR/Purity Lab scale
25 4-Bromomethyl-7-methoxycoumarin  coumarine 35231-44-8 1 Kg COA/NMR/Purity Lab scale
26 3-bromo-7-methoxy-4-methyl-2H-1-benzopyran-2-one coumarine 75908-67-7 100 g COA/NMR/Purity Lab scale
27 1-Nitrosopiperizine nitroso 5632-47-3 100 g COA/NMR/Purity Lab scale
28 2-tert butyldimethylsilyloxy)ethanol Silyl derivative 102229-10-7 1 Kg COA/NMR/Purity Pilot scale
29 Ethyl 4-bromo-3-oxobutanoate aliphatic bromo 13176-46-0 2 Kg COA/NMR/Purity Pilot scale
30 1,1′-Dimethylferrocene ferrocene 1291-47-0 500 g COA/NMR/Purity Lab scale
31 (E)-1-bromo-3,7,11,15-tetramethylhexadec-2-ene terpeniods 4444-13-7 2 Kg COA/NMR/Purity Pilot scale
32 3,3,4,4-tetramethylpyrrolidine-2,5-dione aliphatic 3566-61-8 100 g COA/NMR/Purity Lab scale
33 2-chlorofuran-3-carboxylic acid heterocylic 31491-45-9 10 Kg COA/NMR/Purity Pilot scale
34 allyl diethyl phosphate phosphorus 3066-75-9 500g COA/NMR/Purity Pilot scale
35 tert-butyl (2-chloroethyl)(methyl)carbamate aliphatic 220074-38-4 200g COA/NMR/Purity Pilot scale
36 1,5-dimethyl-4-nitro-1H-imidazole imidazole 7464-68-8 100g COA/NMR/Purity Pilot scale
37 1-benzyl-3-ethylpiperazine piperazine 324750-04-1 100g COA/NMR/Purity Pilot scale
38 tert-butyl 4-hydroxy-3-methyl-1H-indazole-1-carboxylate indazole 1823241-77-5 100g COA/NMR/Purity Pilot scale
39 dimethylpropanedinitrile nitrile 7321-55-3 100g COA/NMR/Purity Pilot scale
40 1,2-dibromocyclopent-1-ene bromo 75415-78-0 100g COA/NMR/Purity Pilot scale
41 5-(2-methylthiazol-4-yl)thiophene-2-carbaldehyde thiazole 499770-66-0 100g COA/NMR/Purity Pilot scale
42 (5-chloropyridin-2-yl)boronic acid boronic acid 652148-91-9 100g COA/NMR/Purity Pilot scale
43 2-isopropoxyphenol phenol 4812-20-8 100g COA/NMR/Purity Pilot scale
44 methyl bis(4-hydroxyphenyl)sulfite sulphite 41481-66-7 100g COA/NMR/Purity Pilot scale
45 methyl 2-methylbenzoate aromatic ester 89-71-4 100g COA/NMR/Purity Pilot scale
46 5-bromopicolinaldehyde pyridine 31181-90-5 100g COA/NMR/Purity Pilot scale
47 tert-butyl (3-hydroxypropyl)carbamate aliphatic boc 58885-58-8 100g COA/NMR/Purity Pilot scale
48 diethyl 2-hydroxymalonate aliphatic 13937-08-1 250 g COA/NMR/Purity Pilot scale
49 2-formyl-4-methoxyphenyl)boronic acid boronic acid 139962-95-1 1 Kg COA/NMR/Purity Pilot scale
50 3-(chloromethyl)-1-methyl-1H-pyrazole hydrochloride pyrazoles 88529-80-0 100g COA/NMR/Purity Pilot scale
51 2,2-difluoro-1,3-dimethyimidazolidine imidazole 220405-40-3 500 g COA/NMR/Purity Pilot scale
52 3-hydroxy pyridine 2-carboxaldehyde pyridine 1849-55-4 50g COA/NMR/Purity Pilot scale
53 1-bromo-3,5-dichlorobenzene chloro bromo derivative 19752-55-7 Pilot scale COA/NMR/Purity
54 3-Bromo-5-chlorobenzotrifluoride chloro bromo derivative 928783-85-1 5 Kg COA/NMR/Purity Pilot scale
55 1-(trifluoroacetyl)piperidine Fluro derivatives 340-07-8 COA/NMR/Purity Pilot scale
56 1-(2-Fluoro-4-(trifluoromethyl)phenyl)cyclopropane car boxylic acid Fluro derivatives 1274902-10-1 30 Kg COA/NMR/Purity Pilot scale

Capabilities and Expertise

Proven expertise (from mg scale to Kg scale till commercial scale)

S.No.
1 Low Temp Reactions : Up to -100 °C
2 High Temp Reactions : Up to +200 °C
3 Metal Reactions : E.g.: Grignard, Na, Li, Pd, Cu etc.
4 Hydrogenation : Pd/C, Rh/C, Ra-Ni, Adam’s Catalyst etc
5 Pyrophoric Reactions : Super Hydride, LAH, NBL, LDA, etc.
6 Pressure Reactions : Seal Tube, Autoclave
7 Cross Coupling : Suzuki, Kumada, Stille, Sonagashira, Heck, Negishi etc.
8 Metasis Reaction : Grubbs etc.
9 Asymetric Synthesis : Chiral Auxiliary, Enantio and Diasterio Selective etc
10 Heterocyclic Synthesis : Pyridine, Pyrimidine, Indole, Indazole, etc.
11 Boronic Acid Synthesis